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An application-based ontological knowledge base of medications to support health literacy and adherence for the consumer population: an aging population use case

2026graph constructionapplicationontology

Clifford Chen, Cui Tao, Rebecca L. Mauldin, Kirk Roberts, Muhammad Amith, Renata Komalasari

Journal of Biomedical Semantics

https://doi.org/10.1186/s13326-026-00347-8OpenAlex: W7126068035
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Abstract Quality
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Problems Identified (5)

Medication non-adherence in geriatrics: The geriatric population is vulnerable to medication non-adherence, which can increase morbidity, mortality, and resource waste.

Poor health literacy: Poor health literacy is identified as one multifactorial reason for patient medication non-adherence.

Patient medication information needs: Consumer and geriatric patients need drug information concepts that can support patient-directed medication tools.

Medication non-adherence in geriatrics: The geriatric population is vulnerable to medication non-adherence, which can increase morbidity, mortality, and resource waste.

Poor health literacy: Poor health literacy is identified as one multifactorial reason for patient medication non-adherence.

Proposed Solutions (5)

Patient-centric Drug Knowledge Graph: The authors created a patient-directed drug information knowledge graph using patient-directed resources and the Vaccine Information Statement Ontology.

Medication-specific PcDKG instances: The authors created five knowledge graph instances under the PcDKG framework for common geriatric medications.

SPARQL question-based coverage assessment: The authors converted common patient questions into SPARQL queries to assess the model's coverage.

Patient-centric Drug Knowledge Graph: The authors created a patient-directed drug information knowledge graph using patient-directed resources and the Vaccine Information Statement Ontology.

Medication-specific PcDKG instances: The authors created five knowledge graph instances under the PcDKG framework for common geriatric medications.

Results (3)

PcDKG size reported:

Five medication graph instances created:

First consumer drug-needs KG claim:

Research Domain

Biomedical semantics / consumer medication knowledge graphs

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